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Alliance Française contre les Maladies Parasitaires

Friday, 17 June 2022

[Communiqué] L'équipe du Dr Chetan Chitnis de l’Institut Pasteur, partenaire du LabEx ParaFrap, a étudié le stade sanguin du parasite Plasmodium falciparum, à l’origine de la forme la...

Thursday, 24 March 2016

The Bioscope Group is organizing the Bioscope Summer Courses in Proteomics in June 2016, in Caparica (Lisbon, Portugal), as follows:   June 15th-17th 2016Hands-on course in ultrafast sample...

Friday, 27 January 2023

[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs...

Monday, 29 February 2016

The SFP (French Society of Parasitology) - SFMM (the French Society of Medical Mycology) annual meeting 2016 will take place in Grenoble from 23 to 25 March 2016. Information and registration on...

Tuesday, 03 January 2023

Le LabEx ParaFrap vous souhaite plein de bonheur, de santé, de science et de succès pour 2023. Première actualité du réseau cette année : les webinaires ParaFrap reprennent en 2023, comme les...

Tuesday, 27 October 2015

The Bioscope Group is organizing the Bioscope Winter Courses in Proteomics in January-February 2016, in Caparica (Lisbon, Portugal), as follows:   January 25th-27th 2016 V Hands-on course in...

Monday, 14 November 2022

[Communiqué] Gerald Spaeth, chef de l'unité "Parasitologie moléculaire et signalisation" à L'institut pasteur Paris, a obtenu une subvention Synergy du Conseil européen de la...

Monday, 02 November 2015

The Nobel Prize in Medicine 2015 was awarded to researchers in epidemiology : William Campbell (Ireland), Satoshi Omura (Japan) and Youyou Tu (China). They were rewarded for their work against...

Home PROJECTS Plateforms

Plateforms

Proteomics (Lille)

One of the main objective of ParaFrap was to get mass spectrometers and to train PhD students and postdocs with proteomic workshops specificaly adapted to molecular parasitology. The P3M platform (Plateforme de Protéomique et Peptides Modifiés) was created with funding of the LabEx ParaFrap and additional financial supports from the FEDER-Region Nord Pas de Calais, Lille Métropole Urban Community and Pasteur Institute of Lille, which provides lab spaces. The platform provides new expert skills and services open to academic and industrial research in:

plateforme proteomique

  • Identification and characterization of post-translational modifications (PTMs)
  • Separation of proteins by liquid chromatography (LC)
  • Separation of proteins on 1D and 2D gel electrophoresis followed by Typhoon 9400 scanning
  • Analysis by Nano LC-ESI-MS/MS, Nano LC-MALDI-MS/MS and absolute quantification of proteins by MRM (Multiple Reaction Monitoring) using the three mass spectrometers Orbitrap Q Exactive, MALDI TOF/TOF Autoflex and TSQ Endura, respectively
  • Identification of Proteins by crossing the data with the protein sequences database with multiple search engines (Mascot, Sequest, OMSSA)

 

P3M allows the development of a key technology for researchers, for technology transfer / dissemination of knowledge and for valorization of discoveries by industrial partners.

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 P3M website

  

Metabolic (Bordeaux)

bruker

The recent development of new NMR methods for measurements, as well as new methods for the analysis and interpretation of complex data sets generated by NMR spectrometry, means that NMR spectrometry approaches are attractive alternatives to MS or that they can be used in combination with MS approaches.

 

The group of Bordeaux led by Frédéric Bringaud is in close connection to an NMR platform with a long-standing expertise on NMR spectrometry to study end-products excreted from carbohydrate and amino acid metabolism in parasites. The platform acquired a new NMR spectrometer (Bruker Avance III 500 HD) with funding from ParaFrap and the Conseil Régional d’Aquitaine, in order to extend its expertise towards quantitative analyses of intracellular metabolites of unicellular parasites. This equipment is operational since July 2015 with an engineer dedicated to its use and maintenance. Half of the use time of this equipment is reserved to the ParaFrap community at preferential cost.

 

Sequencing (Université Aix-Marseille)

The INSERM UMR 906 Unit has received from the Labex Parafrap a participation to the cost of DNA sequencing equipments. These machines will be made available to Parafrap members for their own projects.

The activities of the platform are the followings:

  • In 2015, targeted sequencing, exome sequencing, small genome sequencing
  • In 2016, methylome analysis, RNA sequencing (RNASeq) high through output genotyping.

The available equipments are as follows:

  • January 2015: one Ion Proton; one Ion PGM, One Bioanalyseur
  • January 2016: in addition to the above mentioned equipment, one Quant studio; one pyromark Q24 one Bioruptor + IP-star (Diagenode).
Friday, 16 December 2022

    PostDoc position in Biological Sciences / Biochemistry: Mode of action of antimalarial benzylmenadiones at IBMC, Strasbourg, France  A renewable 1-year postdoctoral...

Friday, 17 June 2022

[Communiqué] L'équipe du Dr Chetan Chitnis de l’Institut Pasteur, partenaire du LabEx ParaFrap, a étudié le stade sanguin du parasite Plasmodium falciparum, à l’origine de la forme la...

Thursday, 24 March 2016

The Bioscope Group is organizing the Bioscope Summer Courses in Proteomics in June 2016, in Caparica (Lisbon, Portugal), as follows:   June 15th-17th 2016Hands-on course in ultrafast sample...

Friday, 27 January 2023

[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs...

Friday, 03 June 2022

  PhD Position in Single Particle Imaging of P. falciparum Knobs Project Leader Prof. Dr. Michael Lanzer (Heidelberg University Hospital, Centre for Infectious Diseases,...

Monday, 29 February 2016

The SFP (French Society of Parasitology) - SFMM (the French Society of Medical Mycology) annual meeting 2016 will take place in Grenoble from 23 to 25 March 2016. Information and registration on...

Tuesday, 03 January 2023

Le LabEx ParaFrap vous souhaite plein de bonheur, de santé, de science et de succès pour 2023. Première actualité du réseau cette année : les webinaires ParaFrap reprennent en 2023, comme les...

Tuesday, 27 October 2015

The Bioscope Group is organizing the Bioscope Winter Courses in Proteomics in January-February 2016, in Caparica (Lisbon, Portugal), as follows:   January 25th-27th 2016 V Hands-on course in...

PROGRAMME DE FORMATION

Programme Doctoral International

Workshops de formation

ACTUALITÉS

Actualités du LabEx
Autres actualités

 

CONTACT

Project Manager: Yoann MILLERIOUX
Contact

Twitter Social Icon Rounded Square Color @ParaFrap #ParaFrap

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