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Alliance Française contre les Maladies Parasitaires

Friday, 17 June 2022

[Communiqué] L'équipe du Dr Chetan Chitnis de l’Institut Pasteur, partenaire du LabEx ParaFrap, a étudié le stade sanguin du parasite Plasmodium falciparum, à l’origine de la forme la...

Thursday, 24 March 2016

The Bioscope Group is organizing the Bioscope Summer Courses in Proteomics in June 2016, in Caparica (Lisbon, Portugal), as follows:   June 15th-17th 2016Hands-on course in ultrafast sample...

Friday, 27 January 2023

[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs...

Monday, 29 February 2016

The SFP (French Society of Parasitology) - SFMM (the French Society of Medical Mycology) annual meeting 2016 will take place in Grenoble from 23 to 25 March 2016. Information and registration on...

Tuesday, 03 January 2023

Le LabEx ParaFrap vous souhaite plein de bonheur, de santé, de science et de succès pour 2023. Première actualité du réseau cette année : les webinaires ParaFrap reprennent en 2023, comme les...

Tuesday, 27 October 2015

The Bioscope Group is organizing the Bioscope Winter Courses in Proteomics in January-February 2016, in Caparica (Lisbon, Portugal), as follows:   January 25th-27th 2016 V Hands-on course in...

Monday, 14 November 2022

[Communiqué] Gerald Spaeth, chef de l'unité "Parasitologie moléculaire et signalisation" à L'institut pasteur Paris, a obtenu une subvention Synergy du Conseil européen de la...

Monday, 02 November 2015

The Nobel Prize in Medicine 2015 was awarded to researchers in epidemiology : William Campbell (Ireland), Satoshi Omura (Japan) and Youyou Tu (China). They were rewarded for their work against...

Home PIs Anna Cohuet

 

  Anna Cohuet

 

 

Anna COHUET

Information
microscope MIVEGEC 
team MoMa (Mosquito X Malaria Interactions) 
location Montpellier
orcid 0000-0002-1876-5656 
email This email address is being protected from spambots. You need JavaScript enabled to view it.
website https://mivegec.fr/
twitter @mivegec 

Scientific interests and projects

I have special interest in the ecology of malaria transmission and I have been working on the genetic and environmental determinants of vectorial capacity and competence in malaria vectors, especially focusing on the An. gambiae - P. falciparum system. An ongoing effort in my group is to account for the natural diversity of vector mosquitoes-malaria parasite associations and to perform experiments in conditions that reflect nature as much as possible. I currently develop my field research projects in Burkina Faso on transmission-blocking interventions and on the behavioral effect of infection in interactions with malaria control tools. I lead the MoMa team (Mosquito-Malaria interactions), which is composed of 5 other permanent members and postdocs and students.

We believe that malaria transmission is best studied through a variety of means combining the relevance of the field and the power of model systems. Therefore, we have developed platforms in Cameroon and Burkina Faso for experimental infection of mosquito vectors by P. falciparum isolates collected from naturally infected patients. For instance, such facilities allow measuring the efficacy of transmission-blocking interventions. Mosquitoes can also be exposed to specific environmental conditions, including exposition to insecticides for measuring their effect, or the insect can be fed before and after a drug treatment by the patient.

In addition, an avian malaria system ( Plasmodium relictum - Culex pipiens ) was developed in Montpellier, which could be especially useful to overcome ethical or technical limitations specific to the inclusion of human patients. Recognising the power of genomics, we are in the midst of adapting our current enquiry methods to the genomics era. We have described the use of single cell transcriptomics directly in parasites from naturally infected carriers, which opens the possibility of studying disease and transmission relevant phenotypes directly in infected patients and bridge the gap between lab and field investigations. We therefore have a rich field and lab experimental scope through which many aspects of malaria biology could be studied within new collaborations.

Top 5 publications of the last 5 years

1. Carrasco D, Lefèvre T, Moiroux N, Pennetier C, Chandre F, Cohuet A. Behavioural adaptations of mosquito vectors to insecticide control. Curr Opin Insect Sci. 2019 Aug;34:48-54. DOI 10.1016/j.cois.2019.03.005.

2. Mulatier M, Camara S, Koffi A, Carrasco D, Porciani A, Chandre F, Moiroux N, Lefevre T, Dabiré R, Assi S, Ahoua Alou LP, Dormont L, Pennetier C, Cohuet A. Efficacy of vector control tools against malaria-infected mosquitoes. Sci Rep. 2019 Apr 30;9(1):6664. DOI 10.1038/s41598-019-43195-6.

3. Stone WJR, Campo JJ, Ouédraogo AL, Meerstein-Kessel L, Morlais I, Da D, Cohuet A, et al. Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity. Nature communications 2018 Feb 8;9(1):558.) DOI 10.1038/s41467-017-02646-2

4. Alout H, Roche B, Dabiré RK, Cohuet A. Consequences of insecticide resistance on malaria transmission. PLoS Pathog. 2017 Sep 7;13(9):e1006499. DOI 10.1371/journal.ppat.1006499

5. Churcher TS, Trape JF, Cohuet A: Human-to-mosquito transmission efficiency increases as malaria is controlled. Nature communications 2015, 6:6054. 10.1038/ncomms7054
Friday, 16 December 2022

    PostDoc position in Biological Sciences / Biochemistry: Mode of action of antimalarial benzylmenadiones at IBMC, Strasbourg, France  A renewable 1-year postdoctoral...

Friday, 17 June 2022

[Communiqué] L'équipe du Dr Chetan Chitnis de l’Institut Pasteur, partenaire du LabEx ParaFrap, a étudié le stade sanguin du parasite Plasmodium falciparum, à l’origine de la forme la...

Thursday, 24 March 2016

The Bioscope Group is organizing the Bioscope Summer Courses in Proteomics in June 2016, in Caparica (Lisbon, Portugal), as follows:   June 15th-17th 2016Hands-on course in ultrafast sample...

Friday, 27 January 2023

[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs...

Friday, 03 June 2022

  PhD Position in Single Particle Imaging of P. falciparum Knobs Project Leader Prof. Dr. Michael Lanzer (Heidelberg University Hospital, Centre for Infectious Diseases,...

Monday, 29 February 2016

The SFP (French Society of Parasitology) - SFMM (the French Society of Medical Mycology) annual meeting 2016 will take place in Grenoble from 23 to 25 March 2016. Information and registration on...

Tuesday, 03 January 2023

Le LabEx ParaFrap vous souhaite plein de bonheur, de santé, de science et de succès pour 2023. Première actualité du réseau cette année : les webinaires ParaFrap reprennent en 2023, comme les...

Tuesday, 27 October 2015

The Bioscope Group is organizing the Bioscope Winter Courses in Proteomics in January-February 2016, in Caparica (Lisbon, Portugal), as follows:   January 25th-27th 2016 V Hands-on course in...

PROGRAMME DE FORMATION

Programme Doctoral International

Workshops de formation

ACTUALITÉS

Actualités du LabEx
Autres actualités

 

CONTACT

Project Manager: Yoann MILLERIOUX
Contact

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